“Clinician-scientist John Younger went one step further than a leave of absence. After partially sidelining his 21-year career in emergency medicine at the University of Michigan (UM), Ann Arbor, in 2014 to develop a micro-bubble cell-capturing technology, he ended up leaving academia completely. ”

“The initial idea was to use tiny spheres tagged with antibodies or other molecules to diagnose sepsis, the body’s life-threatening response to overwhelming infection. The micro-bubbles engage cells or bacteria and float them into an analytical instrument. Over time, the applications expanded into cancer research and diagnostics, and Younger teamed up with physicist-entrepreneur Brandon McNaughton. The two scored an I-Corps slot and came away from the program with the classic entrepreneurial urge. We “had to understand if this could really work,” Younger says. ”

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